2 products were found matching "Cay14661-100"!

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AY 9944
AY 9944

Item number: Cay14611-10

AY 9944 prevents cholesterol biosynthesis by inhibiting the 7-dehydro cholesterol Delta7-reductase (DHCR7) enzyme (IC50 = 13 nM), which interferes with the conversion of 7-dehydro cholesterol (Cay-14612) to cholesterol. Furthermore, by upregulating the expression of DHCR7, AY 9944 can block Hedgehog signaling at the...
Keywords: trans-N1,N4-bis[(2-chlorophenyl)methyl]-1,4-cyclohexanedimethanamine, dihydrochloride
Application: DHCR7 inhibitor
CAS 366-93-8
MW: 464.3 D
From 46.00€ *
Review
AAF-CMK (trifluoroacetate salt)
AAF-CMK (trifluoroacetate salt)

Item number: Cay14461-10

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome....
Keywords: N-Ala-Ala-Phe-CMK, Tripeptidyl Peptidase Inhibitor II,...
Application: TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor
CAS 184901-82-4
MW: 453.8 D
From 84.00€ *
Review