2 products were found matching "Cay14660-25"!

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Item number: Cay14602-5

Mecamylamine is a noncompetitive nicotinic acetylcholine receptor antagonist with preferential activity at the alpha3beta4 subtype (IC50 = 90-640 nM) compared to alpha4beta2, alpha3beta2, and alpha7 subtypes (IC50 range from 1-7 µM). Mecamylamine is widely used as a broad-spectrum antagonist of neuronal nicotinic...

Keywords:	Inversine, N,2,3,3-tetramethyl-bicyclo[2.2.1]heptan-2-amine, monohydrochloride
Application:	Nicotinic acetylcholine receptor antagonist
CAS	826-39-1
MW:	203.8 D

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Sumatriptan (succinate)

Item number: Cay14600-25

Sumatriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s = 9.3 and 7.3 nM, respectively). It also binds to the 5-HT1F receptor (IC50 = 17.8 nM). It induces vasoconstriction in isolated human middle meningeal arteries (EC50 = 89.9 nM), an effect that can be reduced by the 5-HT1B/1D...

Keywords:	GR 43175C, 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide-butanedioic acid
Application:	Serotonin 5-HT1B/D receptor agonist
CAS	103628-48-4
MW:	413.5 D

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