8 products were found matching "Cay15751"!

epi-Testosterone (Cay-15875) is an analytical reference material categorized as an anabolic androgenic steroid. epi-Testosterone has been used as a masking agent for testosterone in sports doping. epi-Testosterone is regulated as a Schedule III compound in the United States. This product is intended for research and...

A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are 2,5-dimethoxy-4-substituted phenethylamines, many are scheduled as illegal substances. 2C-H is described formally as 2,5-dimethoxyphenethylamine. Unlike the 4-substituted 2-C forms, it has...

The Ras family of GTPases, including the Arf, Rho, Ras, and Rab GTPase subfamilies, regulates various cellular processes ranging from membrane trafficking to the control of cell proliferation. They regulate cell physiology by switching between active and inactive conformational states by binding either GTP or GDP....

Metamizole is a nonopioid prodrug that is rapidly hydrolyzed to the analgesic and antipyretic metabolites 4-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA). It inhibits COX-1 and COX-2 activity (IC50 = ~150 µg/ml for both in cell-free assays), as well as reduces increases in intracellular calcium levels...

Apicidin is a cyclic tetrapeptide that has been found in F. pallidoroseum and has diverse biological activities. It is active against E. tenella, T. gondii, P. falciparum, C. parvum, N. caninum, B. jellisoni, and C. bigenetica (MICs = 62, 8, 125, 30, 15, 4, and 8 ng/ml, respectively) and decreases the percentage of...

Podophyllotoxin is a lignan that has been found in Podophyllum and has diverse biological activities. It inhibits polymerization of isolated chicken brain tubulin (IC50 = 0.6 µM) and induces mitotic arrest at the G2/M phase in CCRF CEM lymphoblastic leukemia cells when used at concentrations ranging from 0.01 to 5...

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV, Ki = 4.3 µM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 µM, respectively). PSI-6130 also inhibits replication of HCV...

Calindol is a phenylalkylamine calcimimetic that facilitates the activation of the calcium-sensing receptor (CaSR), a G protein-coupled receptor that triggers phosphatidylinositol (PI)-intracellular calcium signaling and, in some cell types, cell proliferation. It potently stimulates PI hydrolysis and proliferation...