TNF-R1 (human):Fc (human, rec.)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-40B-0074-C050	50 µg		-		3 - 9 business days*		204.00€
AG-40B-0074-3050	150 µg (3 x 50 µg)		-		3 - 9 business days*		407.00€

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(3 x 50µg). The extracellular domain of human TNF-R1 (amino acids 22-211) is fused to the Fc... more

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Product information "TNF-R1 (human):Fc (human, rec.)"

(3 x 50µg). The extracellular domain of human TNF-R1 (amino acids 22-211) is fused to the Fc portion of human IgG1. TNF-R1:Fc fusion protein blocks TNF-alpha-mediated biological effect with an inhibitory activity in a concentration range of 0.1 to 1µg/ml. Lyophilized. Contains PBS. TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Keywords:	p55, CD120a, TNFRSF 1A, Tumor Necrosis Factor Receptor Superfamily Member 1A, TNF Receptor 1
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-40B-0074