Kontakt 0800-2466651 DE | EN Login Warenkorb



Produkttypen



Sonderbestellungen:


Spezifische Suchen:


Treffer 1 print
ART-NR PRODUKT HERSTELLER MENGE PREIS
IMG-2011set
TLR4 Inhibitory Peptide Set (VIPER)
Imgenex
Icon Datasheet
1 set

Buy Bulk

395 €

TLR4 Inhibitory Peptide Set (VIPER)


TLR4 inhibition Erklärungen der Abkürzungen ansehen.

Set contains 1 mg each of VIPER and CP7 (control peptide). VIPER (viral inhibitory peptide of TLR4) is a TLR4 specific inhibitory peptide that potentently inhibits TLR4-mediated responses and is inert towards other TLR pathways (Bowie et al. 2010, Lysakova-Devine et al. 2010). VIPER consists of an 11 amino acid (KYSFKLILAEY)inhibitory sequence, derived from the A46 vaccinia virus protein, linked to a 9R (RRRRRRRRR) homopolymer delivery sequence. VIPER interferes with the interaction between TLR4 and its adaptor proteins Mal and TRAM. It is thought that VIPER inhibits TLR4 signaling by binding to the TIR domains of Mal and TRAM. Since TIR domains engage the MAl and TRAM adaptor proteins with TLR4, blocking adaptor TIR domains with VIPER would disrupt propagation of the TLR4 signal. However, the exact mechanism by which VIPER inhibits TLR4 signaling remains to be fully elucidated. Likewise, the specific VIPER binding sites on TRAM and Mal TIR domains remain to be identified.


UniProt ID: O00206

Loading Loading ...

- Geninformationen GeneID 7099

Weitere Produkte für dieses Protein:

Antibodies

Chemicals & More



Relevant Pathways:



Products for: TLR4 - toll-like receptor 4



Schlagworte:
TLR4, CD284, Toll-​like receptor 4

 

 

Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer
1    


HOT LINKS


Forschungsprodukte im Fokus

 

Produkte

Service

Company

€ 10

Gutschein sichern