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Item number: Cay23282-1

ML-210 is an inhibitor of glutathione peroxidase 4 (GPX4). It reduces viability of mesenchymal-state KP4 cells, an effect that can be blocked by the arachidonic acid lipoxygenase inhibitors PD 146176 (Cay-10010518) and zileuton (Cay-10006967). It is also selectively lethal to mutant RAS oncogene-expressing cells...

Keywords:	DPI10, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone
Application:	HRas(G12V)-expressing cell specific cytotoxin
CAS	1360705-96-9
MW:	475.3 D

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