- Search results for Cay16289
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
4 products were found matching "Cay16289"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay16289-1
TG101348 is a JAK2 inhibitor (IC50 = 3 nM for wild-type and JAK2V617F enzymes). It is 35-, 334-, and 135-fold selective for JAK2 over JAK1, JAK3, and tyrosine kinase 2 (TYK2), respectively. It is also selective for JAK2 over a panel of 34 kinases at 500 nM but does inhibit FMS-related tyrosine kinase 3 (FLT3) and...
Keywords: | Fedratinib, SAR302503,... |
Application: | JAK2 inhibitor |
CAS | 936091-26-8 |
MW: | 524.7 D |
From 77.00€
*
Item number: Cay16089-250
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to...
Keywords: | 4-MU Palmitate, 4-MUP, Palmitoyl 4-Methylumbelliferone, hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester |
Application: | Fluorogenic LAL / Cholesteryl esterase substrate |
CAS | 17695-48-6 |
MW: | 414.6 D |
From 104.00€
*
Item number: Cay16298-1
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 where a switch from valine to phenylalanine occurs at the 617 position (V617F)....
Keywords: | (2S)-N-[4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide |
Application: | JAK2 inhibitor |
CAS | 945755-56-6 |
MW: | 444.5 D |
From 125.00€
*
Item number: Cay16928-5
CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 µg/ml. It is without effect against MMP-1, MMP-9 or TNF-alpha converting enzyme. CL 82,198 is used to evaluate the role of MMP-13 in diverse processes, including cancer cell...
Keywords: | N-[4-(4-morpholinyl)butyl]-2-benzofurancarboxamide |
Application: | MMP-13 inhibitor |
CAS | 307002-71-7 |
MW: | 302.4 D |
From 84.00€
*