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Item number: Cay16289-1

TG101348 is a JAK2 inhibitor (IC50 = 3 nM for wild-type and JAK2V617F enzymes). It is 35-, 334-, and 135-fold selective for JAK2 over JAK1, JAK3, and tyrosine kinase 2 (TYK2), respectively. It is also selective for JAK2 over a panel of 34 kinases at 500 nM but does inhibit FMS-related tyrosine kinase 3 (FLT3) and...

Keywords:	Fedratinib, SAR302503,...
Application:	JAK2 inhibitor
CAS	936091-26-8
MW:	524.7 D

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