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Item number: Cay14994-500

Metyrapone is an inhibitor of the cytochrome P450 (CYP) enzyme 11beta-hydroxylase (IC50 = 7.83 µM), an enzyme involved in the final step of cortisol biosynthesis. It also induces Cyp1a1 and Cyp3a4 expression in rat hepatic microsomes and inhibits the activity of 11beta-hydroxysteroid dehydrogenase type 1...

Keywords:	NSC 25265, SU 4885, 2-methyl-1,2-di-3-pyridinyl-1-propanone
Application:	11beta-hydroxylase inhibitor, CYP450 inhibitor
CAS	54-36-4
MW:	226.3 D

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