- Search results for Cay14494-25
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7 products were found matching "Cay14494-25"!
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Item number: Cay14425-25
Teniposide is a topoisomerase II poison. It promotes calf thymus topoisomerase II-mediated DNA cleavage when used at concentrations ranging from 0.04 to 40 µg/ml. Teniposide induces single- and double-stranded DNA breaks in a concentration-dependent manner. It inhibits the proliferation of A549 lung cancer cells...
Keywords: | NSC 122819, VM-26,... |
Application: | Topoisomerase II inhibitor |
CAS | 29767-20-2 |
MW: | 656.7 D |
From 43.00€
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Item number: Cay14424-50
Darifenacin is an antagonist of M3 muscarinic acetylcholine receptors (mAChRs, Ki = 0.76 nM). It is selective for M3 over M1, M2, M4, and M5 mAChRs (Kis = 7.08, 44.67, 45.71, and 9.33 nM, respectively). Darifenacin selectively inhibits contractions in isolated guinea pig ileum, bladder, and trachea (pA2s = 9.44,...
Keywords: | UK 88525-04, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-3-pyrrolidineacetamide, monohydrobromide |
Application: | Muscarinic receptor antagonist |
CAS | 133099-07-7 |
MW: | 507.5 D |
From 92.00€
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Item number: Cay14449-25
Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: | Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole |
Application: | MAO inhibitor |
CAS | 17019-01-1 |
MW: | 216.3 D |
From 62.00€
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Item number: Cay14944-250
HMG-CoA reductase (HMGR) is a highly regulated enzyme found on the endoplasmic reticulum (ER) membrane. It is bound to the ER membrane by a multi-pass 339 amino acid N-terminal transmembrane domain while the carboxy terminal catalytic region projects into the cytosol. HMGR is controlled by feedback regulation from...
Keywords: | HMG-CoA reductase, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxy-3-methylglutaryl-coenzyme... |
Application: | Enzyme activity |
Origin: | human |
MW: | 76.5 kD |
409.00€
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Item number: Cay14499-25
Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: | 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo... |
Application: | Antibiotic |
CAS | 3513-03-9 |
MW: | 458.9 D |
From 54.00€
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Item number: Cay14498-25
Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: | ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt |
Application: | Kinase / adenylate cyclase substrate, Metabolic studies |
CAS | 987-65-5 |
MW: | 551.1 D |
From 77.00€
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Item number: Cay14497-25
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: | N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 681136-29-8 |
MW: | 365.5 D |
From 98.00€
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