7 products were found matching "Cay14494-25"!

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Teniposide
Teniposide

Item number: Cay14425-25

Teniposide is a topoisomerase II poison. It promotes calf thymus topoisomerase II-mediated DNA cleavage when used at concentrations ranging from 0.04 to 40 µg/ml. Teniposide induces single- and double-stranded DNA breaks in a concentration-dependent manner. It inhibits the proliferation of A549 lung cancer cells...
Keywords: NSC 122819, VM-26,...
Application: Topoisomerase II inhibitor
CAS 29767-20-2
MW: 656.7 D
From 43.00€ *
Review
Darifenacin (hydrobromide)
Darifenacin (hydrobromide)

Item number: Cay14424-50

Darifenacin is an antagonist of M3 muscarinic acetylcholine receptors (mAChRs, Ki = 0.76 nM). It is selective for M3 over M1, M2, M4, and M5 mAChRs (Kis = 7.08, 44.67, 45.71, and 9.33 nM, respectively). Darifenacin selectively inhibits contractions in isolated guinea pig ileum, bladder, and trachea (pA2s = 9.44,...
Keywords: UK 88525-04, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-3-pyrrolidineacetamide, monohydrobromide
Application: Muscarinic receptor antagonist
CAS 133099-07-7
MW: 507.5 D
From 92.00€ *
Review
Tetrahydroharmine
Tetrahydroharmine

Item number: Cay14449-25

Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole
Application: MAO inhibitor
CAS 17019-01-1
MW: 216.3 D
From 62.00€ *
Review
HMG-CoA Reductase (human recombinant)
HMG-CoA Reductase (human recombinant)

Item number: Cay14944-250

HMG-CoA reductase (HMGR) is a highly regulated enzyme found on the endoplasmic reticulum (ER) membrane. It is bound to the ER membrane by a multi-pass 339 amino acid N-terminal transmembrane domain while the carboxy terminal catalytic region projects into the cytosol. HMGR is controlled by feedback regulation from...
Keywords: HMG-CoA reductase, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxy-3-methylglutaryl-coenzyme...
Application: Enzyme activity
Origin: human
MW: 76.5 kD
409.00€ *
Review
Blasticidin S (hydrochloride)
Blasticidin S (hydrochloride)

Item number: Cay14499-25

Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo...
Application: Antibiotic
CAS 3513-03-9
MW: 458.9 D
From 54.00€ *
Review
Adenosine 5'-triphosphate (sodium salt)
Adenosine 5'-triphosphate (sodium salt)

Item number: Cay14498-25

Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt
Application: Kinase / adenylate cyclase substrate, Metabolic studies
CAS 987-65-5
MW: 551.1 D
From 77.00€ *
Review
JNJ-1661010
JNJ-1661010

Item number: Cay14497-25

Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide
Application: FAAH inhibitor
CAS 681136-29-8
MW: 365.5 D
From 98.00€ *
Review