17 products were found matching "Cay14495"!

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Ondansetron (hydrochloride hydrate)
Ondansetron (hydrochloride hydrate)

Item number: Cay14999-5

Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...
Keywords: 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate
Application: Analytical reference material, Serotonin 5-HT3 receptor antagonist, Antiemetic
CAS 103639-04-9
MW: 365.9 D
84.00€ *
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Obatoclax (mesylate)
Obatoclax (mesylate)

Item number: Cay11499-5

Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and...
Keywords: GX15-070, 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate
Application: Antagonist of Bcl-2 family members containing four Bcl-2 homology domains
CAS 803712-79-0
MW: 413.5 D
From 84.00€ *
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Tetrahydroharmine
Tetrahydroharmine

Item number: Cay14449-5

Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole
Application: MAO inhibitor
CAS 17019-01-1
MW: 216.3 D
From 62.00€ *
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Cediranib
Cediranib

Item number: Cay11495-5

Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and...
Keywords: AZD 2171, ZD 2171, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-quinazoline
Application: VEGFR1/2/3 inhibitor
CAS 288383-20-0
MW: 450.5 D
From 119.00€ *
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HA-100 (hydrochloride)
HA-100 (hydrochloride)

Item number: Cay14955-10

HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).Formal Name:...
Keywords: C-1, 5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride
Application: Protein kinase inhbitor
CAS 210297-47-5
MW: 350.3 D
From 85.00€ *
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17-trans Prostaglandin E3
17-trans Prostaglandin E3

Item number: Cay14995-50

17-trans Prostaglandin E3 (17-trans PGE3) is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.Formal Name: 11alpha,15S-dihydroxy-9-oxo-prosta-5Z,13E,17E-trien-1-oic acid. CAS Number:...
Keywords: 17-trans PGE3, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E,17E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 210979-33-2
MW: 350.5 D
From 115.00€ *
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Adenosine 5'-triphosphate (sodium salt)
Adenosine 5'-triphosphate (sodium salt)

Item number: Cay14498-5

Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt
Application: Kinase / adenylate cyclase substrate, Metabolic studies
CAS 987-65-5
MW: 551.1 D
From 77.00€ *
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N-Phenylacetyl-L-Prolylglycine ethyl ester
N-Phenylacetyl-L-Prolylglycine ethyl ester

Item number: Cay14496-5

N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester
Application: Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory
CAS 157115-85-0
MW: 318.4 D
From 84.00€ *
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JNJ-1661010
JNJ-1661010

Item number: Cay14497-5

Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide
Application: FAAH inhibitor
CAS 681136-29-8
MW: 365.5 D
From 98.00€ *
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Blasticidin S (hydrochloride)
Blasticidin S (hydrochloride)

Item number: Cay14499-25

Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo...
Application: Antibiotic
CAS 3513-03-9
MW: 458.9 D
From 54.00€ *
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SGC-CBP30
SGC-CBP30

Item number: Cay14469-5

cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and...
Keywords: 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-4-isoxazolyl)-1-[(2S)-2-(4-morpholinyl)propyl]-1H-benzimidazole
Application: CREBBP / EP300 bromodomain inhibitor
CAS 1613695-14-9
MW: 509 D
From 147.00€ *
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ZCL 278
ZCL 278

Item number: Cay14849-5

ZCL 278 is a cell-permeable inhibitor of Cdc42, a Rho family GTPase. It binds into the surface groove on Cdc42 (Kd = 6.4-11.4 µM), blocking interaction with intersectin (ITSN), a guanine nucleotide exchange factor (GEF). It inhibits Cdc42-mediated microspike formation and neuronal branching in 3T3 fibroblast and...
Keywords: 2-(4-bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-acetamide
Application: Cdc42 inhibitor
CAS 587841-73-4
MW: 584.9 D
From 64.00€ *
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