- Search results for Cay14495
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17 products were found matching "Cay14495"!
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Item number: Cay14999-5
Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...
Keywords: | 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate |
Application: | Analytical reference material, Serotonin 5-HT3 receptor antagonist, Antiemetic |
CAS | 103639-04-9 |
MW: | 365.9 D |
84.00€
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Item number: Cay11499-5
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and...
Keywords: | GX15-070, 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate |
Application: | Antagonist of Bcl-2 family members containing four Bcl-2 homology domains |
CAS | 803712-79-0 |
MW: | 413.5 D |
From 84.00€
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Item number: Cay14449-5
Tetrahydroharmine (THH) is a fluorescent indole alkaloid extracted from B. caapi, a woody vine that is used to produce a psychoactive beverage, ayahuasca, which has been ritually ingested for medicoreligious purposes throughout South America since pre-Columbian times. THH inhibits monoamine oxidase (MAO)-A and MAO-B...
Keywords: | Leptaflorine, THH, 2,3,4,9-tetrahydro-7-methoxy-1-methyl-1H-pyrido[3,4-b]indole |
Application: | MAO inhibitor |
CAS | 17019-01-1 |
MW: | 216.3 D |
From 62.00€
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Item number: Cay11495-5
Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and...
Keywords: | AZD 2171, ZD 2171, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-quinazoline |
Application: | VEGFR1/2/3 inhibitor |
CAS | 288383-20-0 |
MW: | 450.5 D |
From 119.00€
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Item number: Cay14955-10
HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 µM).Formal Name:...
Keywords: | C-1, 5-(1-piperazinylsulfonyl)-isoquinoline, dihydrochloride |
Application: | Protein kinase inhbitor |
CAS | 210297-47-5 |
MW: | 350.3 D |
From 85.00€
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Item number: Cay14995-50
17-trans Prostaglandin E3 (17-trans PGE3) is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids. There are no published reports on the biological activity of this compound.Formal Name: 11alpha,15S-dihydroxy-9-oxo-prosta-5Z,13E,17E-trien-1-oic acid. CAS Number:...
Keywords: | 17-trans PGE3, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E,17E-trien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 210979-33-2 |
MW: | 350.5 D |
From 115.00€
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Item number: Cay14498-5
Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions. ATP is a substrate for kinases involved in cell signaling and of adenylate cyclases that produce...
Keywords: | ATP, NSC 20268, adenosine 5'-(tetrahydrogen triphosphate), disodium salt |
Application: | Kinase / adenylate cyclase substrate, Metabolic studies |
CAS | 987-65-5 |
MW: | 551.1 D |
From 77.00€
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Item number: Cay14496-5
N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: | GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester |
Application: | Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory |
CAS | 157115-85-0 |
MW: | 318.4 D |
From 84.00€
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Item number: Cay14497-5
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines, including the endocannabinoid arachidonoyl ethanolamide (AEA). JNJ-1661010 is a selective inhibitor of FAAH (IC50s = 34 and 33 nM in rat and human, respectively) that is able to cross the blood-brain barrier. At 20 mg/kg, JNJ-1661010 has been shown to...
Keywords: | N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide |
Application: | FAAH inhibitor |
CAS | 681136-29-8 |
MW: | 365.5 D |
From 98.00€
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Item number: Cay14499-25
Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes. The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule. It has since been...
Keywords: | 4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeo... |
Application: | Antibiotic |
CAS | 3513-03-9 |
MW: | 458.9 D |
From 54.00€
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Item number: Cay14469-5
cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and...
Keywords: | 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-4-isoxazolyl)-1-[(2S)-2-(4-morpholinyl)propyl]-1H-benzimidazole |
Application: | CREBBP / EP300 bromodomain inhibitor |
CAS | 1613695-14-9 |
MW: | 509 D |
From 147.00€
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Item number: Cay14849-5
ZCL 278 is a cell-permeable inhibitor of Cdc42, a Rho family GTPase. It binds into the surface groove on Cdc42 (Kd = 6.4-11.4 µM), blocking interaction with intersectin (ITSN), a guanine nucleotide exchange factor (GEF). It inhibits Cdc42-mediated microspike formation and neuronal branching in 3T3 fibroblast and...
Keywords: | 2-(4-bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-acetamide |
Application: | Cdc42 inhibitor |
CAS | 587841-73-4 |
MW: | 584.9 D |
From 64.00€
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