- Search results for Cay11922-100
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4 products were found matching "Cay11922-100"!
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Item number: Cay11992-10
Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...
Keywords: | N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester |
Application: | mGluR1 modulator |
CAS | 302841-89-0 |
MW: | 325.4 D |
From 43.00€
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Item number: Cay19922-10
Ozanimod is a sphingosine-1-phosphate receptor 1 (S1P1) and S1P5 agonist. It induces GTPgammaS binding in cell membranes expressing human S1P1 or S1P5 (EC50s = 0.41 and 11 nM, respectively) but not cell membranes expressing S1P2 or S1P3 receptors (EC50s = >10,000 nM for both). Ozanimod (0.2 mg/kg) reduces the number...
Keywords: | 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-benzonitrile |
Application: | S1PR1 / S1PR5 modulator, Immunomodulator |
CAS | 1306760-87-1 |
MW: | 404.5 D |
From 60.00€
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Item number: Cay19992-10
CCT007093 is an inhibitor of protein phosphatase 1D (PPM1D, also known as PP2Cdelta and WIP1, IC50 = 8.4 µM), which is encoded by a putative oncogene that is amplified in multiple cancer types. It does not inhibit PPM1A. CCT007093 selectively inhibits the growth of cancer cells that overexpress PPM1D, including...
Keywords: | 2E,5E-bis(2-thienylmethylene)-cyclopentanone |
Application: | PPM1D inhibitor |
CAS | 176957-55-4 |
MW: | 272.4 D |
From 43.00€
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Item number: Cay19210-1
3',4'-dimethyl-alpha-Ethylaminovalerophenone (hydrochloride) (Cay-19210) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.Formal Name:...
Keywords: | 3,4-dimethyl-alpha-Ethylaminopentiophenone, 1-(3,4-dimethylphenyl)-2-(ethylamino)-1-pentanone, monohydrochloride |
Application: | Analytical reference standard, Cathinone, Physiological/toxicological properties unknown |
CAS | 2748485-09-6 |
MW: | 269.8 D |
From 280.00€
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