4 products were found matching "Cay11922-100"!

No results were found for the filter!
Ro 67-4853
Ro 67-4853

Item number: Cay11992-10

Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...
Keywords: N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester
Application: mGluR1 modulator
CAS 302841-89-0
MW: 325.4 D
From 43.00€ *
Review
Ozanimod
Ozanimod

Item number: Cay19922-10

Ozanimod is a sphingosine-1-phosphate receptor 1 (S1P1) and S1P5 agonist. It induces GTPgammaS binding in cell membranes expressing human S1P1 or S1P5 (EC50s = 0.41 and 11 nM, respectively) but not cell membranes expressing S1P2 or S1P3 receptors (EC50s = >10,000 nM for both). Ozanimod (0.2 mg/kg) reduces the number...
Keywords: 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-benzonitrile
Application: S1PR1 / S1PR5 modulator, Immunomodulator
CAS 1306760-87-1
MW: 404.5 D
From 60.00€ *
Review
CCT007093
CCT007093

Item number: Cay19992-10

CCT007093 is an inhibitor of protein phosphatase 1D (PPM1D, also known as PP2Cdelta and WIP1, IC50 = 8.4 µM), which is encoded by a putative oncogene that is amplified in multiple cancer types. It does not inhibit PPM1A. CCT007093 selectively inhibits the growth of cancer cells that overexpress PPM1D, including...
Keywords: 2E,5E-bis(2-thienylmethylene)-cyclopentanone
Application: PPM1D inhibitor
CAS 176957-55-4
MW: 272.4 D
From 43.00€ *
Review
3',4'-dimethyl-alpha-Ethylaminovalerophenone (hydrochloride)
3',4'-dimethyl-alpha-Ethylaminovalerophenone (hydrochloride)

Item number: Cay19210-1

3',4'-dimethyl-alpha-Ethylaminovalerophenone (hydrochloride) (Cay-19210) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.Formal Name:...
Keywords: 3,4-dimethyl-alpha-Ethylaminopentiophenone, 1-(3,4-dimethylphenyl)-2-(ethylamino)-1-pentanone, monohydrochloride
Application: Analytical reference standard, Cathinone, Physiological/toxicological properties unknown
CAS 2748485-09-6
MW: 269.8 D
From 280.00€ *
Review