- Search results for Cay13412-1
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6 products were found matching "Cay13412-1"!
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Item number: Cay34121-10
DM4 is a thiol-containing derivative of the tubulin polymerization inhibitor maytansine. It is cytotoxic to SK-BR-3 cells (IC50 = 3.3 nM). DM4, conjugated to a humanized CD205-targeting monoclonal antibody, is selectively cytotoxic to a variety of CD205-expressing human cancer cells (EC50s = 0.1-1.32 nM) over...
Keywords: | Maytansinoid DM 4, N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine, hydrate |
Application: | Maytansine derivative |
MW: | 780.4 D |
From 130.00€
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Item number: Cay13121-100
Sodium butyrate is a short-chain fatty acid. It is produced predominately by bacterial fermentation of dietary fiber in the colon but has also been identified in mammalian milk. Sodium butyrate is an inhibitor of histone deacetylase (HDAC, IC50 = 90 µM in a cell-free assay). It induces differentiation, cell cycle...
Keywords: | Butyric Acid, butanoic acid, sodium salt |
Application: | HDAC inhibitor |
CAS | 156-54-7 |
MW: | 110.1 D |
From 43.00€
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Item number: Cay14121-10
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. ZLN005 is a small molecule that stimulates...
Keywords: | 2-[4-(1,1-dimethylethyl)phenyl]-1H-benzimidazole |
Application: | PGC-1alpha expression stimulator |
CAS | 49671-76-3 |
MW: | 250.3 D |
From 50.00€
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Item number: Cay21341-5
Ensartinib is a potent and selective inhibitor of anaplastic lymphoma kinase (ALK, IC50 50 = 15 nM) but has no effect on cell growth driven by other mutant kinases or that of non-cancerous HepG2 cells. Ensartinib, at a dose of 25 mg/kg, reduces H3122 xenograft growth with no effect on body weight in nude mice. It is...
Keywords: | 6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-3-pyridazinecarboxamide |
Application: | ALK inhibitor |
CAS | 1365267-27-1 |
MW: | 547.4 D |
From 43.00€
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Item number: Cay13241-5
(±)-CP 55,940 (Cay-13241) is an analytical reference standard categorized as a synthetic cannabinoid. It induces self-administration of morphine in rats. This product is intended for research and forensic applications.Formal Name:...
Keywords: | rel-5-(1,1-dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-phenol |
Application: | CB receptor agonist |
CAS | 83003-12-7 |
MW: | 376.6 D |
From 109.00€
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Item number: Cay13452-10
Oleoyl ethanolamide (OEA) is an endogenous agonist for proliferator-activated receptor alpha (PPARalpha) that suppresses food intake, promotes lipolysis, and reduces weight gain in rodents. The biological effects of OEA are terminated by fatty-acid amide hydrolase and N-acylethanolamine-hydrolyzing acid amidase....
Keywords: | KDS-5104, N-[(1R)-2-hydroxy-1-methylethyl-9Z-octadecenamide |
Application: | PPARalpha activator |
CAS | 213182-22-0 |
MW: | 339.6 D |
From 60.00€
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