- Search results for Cay16805
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10 products were found matching "Cay16805"!
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Item number: Cay16805-5
Sulindac (Cay-10004386) is a non-steroidal anti-inflammatory drug that has an extensive epidemiology documenting reduced human colorectal cancer. In mouse models, sulindac was found not only to inhibit the enzymatic activity of polyp-associated COX-2, but also to downregulate the expression of colonic COX-2 protein...
Keywords: | Exisulind, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor |
CAS | 59864-04-9 |
MW: | 372.4 D |
From 62.00€
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Item number: Cay16800-5
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
Keywords: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
Application: | PI3K gamma / delta inhibitor |
CAS | 1201438-56-3 |
MW: | 416.9 D |
From 92.00€
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Item number: Cay16680-5
Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Cay-16681), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered...
Keywords: | 13,14-dihydro-15-keto-20-ethyl PGF2alpha, 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2alpha,... |
Application: | Bioactive lipid assays |
CAS | 120373-36-6 |
MW: | 382.5 D |
From 82.00€
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Item number: Cay16880-5
Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and...
Keywords: | 5'-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt |
Application: | Nonhydrolyzable GTP analog |
CAS | 64564-03-0 |
MW: | 545.9 D |
From 64.00€
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Item number: Cay16803-5
Luminol is a cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation. For example, HRP, combined with hydrogen peroxide as an activator, causes luminescent peroxidation of luminol. This reaction can be enhanced by certain phenol derivatives, such as p-substituted phenols. Luminol can also be oxidized,...
Keywords: | 3-Aminophthalhydrazide, NSC 5064, 5-amino-2,3-dihydro-1,4-phthalazinedione |
Application: | Chemiluminescence |
CAS | 521-31-3 |
MW: | 177.2 D |
From 60.00€
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Item number: Cay16808-5
Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein...
Keywords: | DBF, NSC 645658, 2-[3-oxo-6-(phenylmethoxy)-3H-xanthen-9-yl]-benzoic acid, phenylmethyl ester |
Application: | Fluorogenic probe, cytochrome P450 substrate |
CAS | 97744-44-0 |
MW: | 512.6 D |
From 60.00€
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Item number: Cay16802-5
CFSE is a fluorescent product of CFDA-SE (Cay-14456) cleavage by intracellular esterases. CFSE lacks the diacetate groups of CFDA-SE and, as a result, is less cell permeable. CFSE fluorescence is cytoplasmic, and it has excitation/emission maxima of 491 and 518 nm, respectively. It covalently couples to...
Keywords: | 5-Carboxyfluorescein NHS ester, 5-Carboxyfluorescein N-Succinimidyl ester, 5-Carboxyfluorescein-N-hydroxysuccinimide... |
Application: | Cell-permeable green fluorescent dye, Cell labeling |
CAS | 92557-80-7 |
MW: | 473.4 D |
From 121.00€
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Item number: Cay16801-5
3-deoxy Galactosone is a 1,2-dicarbonyl compound originating from the degradation of galactose. It can be formed by Maillard or caramelization reactions. 3-deoxy Galactosone has been detected in various food items, including milk, apple juice, and beer, as well as in heat-sterilized dialysis fluids.Formal Name:...
Keywords: | 3-deoxy-D-threo-hexos-2-ulose |
Application: | Galactose degradation product, Maillard reaction product |
CAS | 4134-97-8 |
MW: | 162.1 D |
From 92.00€
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Item number: Cay16804-5
Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole, a triazole derivative, is an inhibitor of brassinosteroid biosynthesis that has been developed in order to probe the myriad functions of...
Keywords: | beta-[(4-chlorophenyl)methyl]-alpha-methyl-alpha-phenyl-1H-1,2,4-triazole-1-ethanol |
Application: | Brassinosteroid biosynthesis inhibitor |
CAS | 224047-41-0 |
MW: | 327.8 D |
From 84.00€
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Item number: Cay16980-5
UK 5099 is a potent inhibitor of the mitochondrial pyruvate carrier (MPC) that inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50 = 50 nM). It decreases glucose flux to the TCA cycle and increases production of M6 citrate via glutaminolytic flux through malic enzymes without affecting...
Keywords: | 2-cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid |
Application: | MPC1 / MPC2 inhibitor |
CAS | 56396-35-1 |
MW: | 288.3 D |
From 43.00€
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