- Search results for Cay16545
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12 products were found matching "Cay16545"!
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Item number: Cay16554-5
Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) alpha (IC50 = 33.1 nM) and an agonist/antagonist for ERbeta (IC50 = 180.5 nM). It also demonstrates ionophoretic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria,...
Keywords: | 4-hydroxy-benzoic acid, (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl... |
Application: | Estrogen receptor alpha agonist, estrogen receptor beta antagonist / agonist |
CAS | 41743-44-6 |
MW: | 358.5 D |
From 53.00€
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Item number: Cay16545-1
Streptavidin conjugated to Alkaline Phosphatase Binding Moiety: Streptavidin Enzyme: Alkaline Phosphatase Reactivity: Biotin Uses: ELISA and Western blot detection Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.Formulation: (Request formulation change), A lyophilized powder. Applications: ELISA, WB.
Application: | ICC, IHC |
161.00€
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Item number: Cay16547-5
Norgestimate is a progestin and a prodrug form of norelgestromin and levonorgestrel (Cay-10006318). It binds to progestin receptors (mean IC50 = 3.48 nM for rabbit uterine receptors) and is selective for progestin over androgen receptors (mean IC50 = 764 nM for rat prostatic receptors) in radioligand binding assays....
Keywords: | Dexnorgestrel acetime, ORF 10131, (17alpha)-17-(acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime |
Application: | Progesterone receptor ligand |
CAS | 35189-28-7 |
MW: | 369.5 D |
From 43.00€
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Item number: Cay16549-5
alpha-Zearalenol is a mycotoxin, an agonist of estrogen receptor alpha (ERalpha), and an active metabolite of zearalenone (Cay-11353). alpha-Zearalenol increases the proliferation of MCF-7 cells that endogenously express ERalpha (EC50 = 0.06 nM). It is also an androgen receptor antagonist (IC50 = 4,170 nM for the...
Keywords: | (3S,7R,11E)-3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one |
Application: | Estrogen receptor agonist, mycotoxin |
CAS | 36455-72-8 |
MW: | 320.4 D |
From 92.00€
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Item number: Cay16548-5
D-Glucose is phosphorylated by glucokinase and three tissue-specific hexokinases to produce glucose-6-phosphate in humans. D-Mannoheptulose is a heptose that inhibits glucokinases and hexokinases from diverse organisms through competition with D-glucose (Ki = 0.25 mM). It blocks glucose oxidation and...
Keywords: | NSC 226836, D-manno-2-heptulose |
Application: | Glucokinase / hexokinase inhibitor |
CAS | 3615-44-9 |
MW: | 210.2 D |
From 66.00€
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Item number: Cay16954-5
Indole-3-acetic acid is an auxin plant growth regulator that is found in all higher-order plants. It reduces plant height and shoot growth in tomato plants when used at concentrations of 10 and 50 µM. Root saturation with indole-3-acetic acid-loaded nanoparticles increases rooting efficiency in P....
Keywords: | Heteroauxin, IAA, 1H-indole-3-acetic acid, monosodium salt |
Application: | Plant hormone |
CAS | 6505-45-9 |
MW: | 197.2 D |
From 43.00€
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Item number: Cay16154-5
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that up-regulates many xenobiotic metabolizing enzymes, particularly in response to planar aromatic hydrocarbons. CH 223191 is a potent and specific antagonist of AhR that blocks activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD,...
Keywords: | 1-methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide |
Application: | Aryl hydrocarbon receptor (AhR) antagonist |
CAS | 301326-22-7 |
MW: | 333.4 D |
From 81.00€
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Item number: Cay16454-5
Medetomidine is an agonist of alpha2-adrenergic receptors (alpha2-ARs, Ki = 1.08 nM). It is selective for alpha2-ARs over alpha1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs. Formulations containing medetomidine have been used as sedatives in veterinary medicine. This product is also available as an...
Keywords: | Domitor(R), MPV 785, 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
Application: | alpha2-adrenergic receptor agonist |
CAS | 86347-15-1 |
MW: | 236.7 D |
From 84.00€
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Item number: Cay16534-5
NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. The half-life of NOC-5 in PBS (pH 7.4) is 93 minutes at 22°C, and it remains relatively stable in alkaline solution (pH >10.0).Formal Name:...
Keywords: | 3-[2-hydroxy-1-(1-methylethyl)-2-nitrosohydrazinyl]-1-propanamine |
Application: | NO donor |
CAS | 146724-82-5 |
MW: | 176.2 D |
From 60.00€
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Item number: Cay16254-5
GNF-5 is an allosteric inhibitor of Bcr-Abl (IC50 = 0.121 µM) and a derivative of GNF-2 (Cay-16253). It also inhibits the Bcr-Abl mutants Bcr-AblG250E, Bcr-AblE255V, and Bcr-AblM351T (IC50s = 4.52, 0.38, and 0.93 µM, respectively). GNF-5 inhibits the growth of Ba/F3 cells (IC50 = 0.145 µM). It reduces viral titers...
Keywords: | N-(2-hydroxyethyl)-3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-benzamide |
Application: | BCR-Abl inhibitor |
CAS | 778277-15-9 |
MW: | 418.4 D |
From 50.00€
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Item number: Cay16354-5
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1, IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases. It effectively blocks signaling through VEGFR2 both in vitro and in vivo. SU 1498 is used to study the role of VEGFR2...
Keywords: | AG-1498, Tyrphostin SU 1498, (2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide |
Application: | VEGFR2 inhibitor |
CAS | 168835-82-3 |
MW: | 390.5 D |
From 46.00€
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Item number: Cay16754-5
Bialaphos is a natural non-selective phytotoxin produced by certain Streptomyces species. It is a pro-toxin, a tripeptide that is converted in vivo to the active agent phosphinothricin, which is a glutamine analog. L-Phosphinothricin inhibits glutamine synthetase (Ki = 6.1 µM), resulting in accumulation of ammonium...
Keywords: | SF 1293, 2S-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine, monosodium salt |
Application: | Glutamine synthetase inhibitor, Selection marker |
CAS | 71048-99-2 |
MW: | 345.3 D |
From 82.00€
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