- Search results for Cay13410
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7 products were found matching "Cay13410"!
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Item number: Cay13334-10
Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 µM) and calcium/calmodulin kinase II...
Keywords: | BIM IX, Ro 31-8220, carbamimidothioic acid,... |
Application: | PKC inhibitor |
CAS | 138489-18-6 |
MW: | 553.7 D |
From 60.00€
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Item number: Cay13344-10
Mitogen-activated protein kinases (MAPKs) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Keywords: | PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine, monohydrochloride |
Application: | p38 MAPK inhibitor |
CAS | 869185-85-3 |
MW: | 413.9 D |
From 149.00€
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Item number: Cay11344-100
PGDM-d4 is intended for use as an internal standard for the quantification of PGDM by GC- or LC-MS. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM...
Keywords: | Prostaglandin D Metabolite-d4, 9alpha,11beta-dihydroxy-15-oxo-13,14-dihydro-2,3,18,19-tetranor-prostan-1,20-dioic... |
Application: | PGDM quantification |
MW: | 332.4 D |
From 237.00€
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Item number: Cay11334-10
An anthroquinone derivative that is naturally found in the flower of H. perforatum (St. John's wort) and has antidepressant, antiviral, and anticancer activities. Hypericin inhibits neuronal uptake of serotonin, norepinephrine, dopamine, GABA and L-glutamate, contributing to its antidepressant effects. It exerts...
Keywords: | NSC 407313, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-phenanthro[1,10,9,8-opqra]perylene-7,14-dione |
Application: | St. John's wort component |
CAS | 548-04-9 |
MW: | 504.5 D |
From 34.00€
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Item number: Cay13452-10
Oleoyl ethanolamide (OEA) is an endogenous agonist for proliferator-activated receptor alpha (PPARalpha) that suppresses food intake, promotes lipolysis, and reduces weight gain in rodents. The biological effects of OEA are terminated by fatty-acid amide hydrolase and N-acylethanolamine-hydrolyzing acid amidase....
Keywords: | KDS-5104, N-[(1R)-2-hydroxy-1-methylethyl-9Z-octadecenamide |
Application: | PPARalpha activator |
CAS | 213182-22-0 |
MW: | 339.6 D |
From 60.00€
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Item number: Cay13453-10
LH 21 is a 1,2,4-triazole that acts as a cannabimimetic. It has a relatively low-affinity for the central cannabinoid (CB1) receptor (Ki = 855 nM). However, it interferes, at low nanomolar concentrations, with the action of the potent CB1 agonist WIN 55,212-2 on murine vas deferens, suggesting that LH 21 acts as a...
Keywords: | 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole |
Application: | CB1 antagonist |
CAS | 611207-11-5 |
MW: | 408.8 D |
From 81.00€
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Item number: Cay13450-10
11beta-Prostaglandin E1 (11beta-PGE1) is an epimerized form of PGE1 at the C-11 position. 11beta-PGE1 is a less potent isomer of PGE1. It is 13% and 3.6% as potent as PGE1 in contracting the rat uterus and guinea pig ileum, respectively.Formal Name: 9-oxo-11beta,15S-dihydroxy-prost-13E-en-1-oic acid. CAS Number:...
Keywords: | 11-epi PGE1, 11beta-PGE1, 9-oxo-11beta,15S-dihydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 24570-01-2 |
MW: | 354.5 D |
From 109.00€
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