10 products were found matching "Cay10348-10"!

Grosvenorine is a flavonol glycoside that has been found in S. grosvenorii and has antibacterial and antioxidant activities. It is active against methicillin-sensitive and -resistant S. aureus, as well as Enterococcus, in disc diffusion assays when used at a concentration of 250 µg/ml. Grosvenorine scavenges ABTS...

gamma-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin is a gamma-aminobutyric acid (GABA) analogue that acts as an anticonvulsant with proven analgesic effects in various neuropathic pain syndromes such as Complex...

9(Z),11(E),13(E)-Octadecatrienoic Acid (alpha-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. alpha-ESA is metabolized and converted to conjugated linoleic...

omega-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. omega-3 Fatty acids are known to be essential for infant growth and development and they protect against heart disease, thrombosis, hypertension, as well as inflammatory and autoimmune disorders. In human...

Sphingosine kinase (SPHK) is an important enzyme in the sphingolipid metabolic pathway. SPHKs phosphorylate D-erythro-sphingosine to yield sphingosine-1-phosphate (S1P). To date two isoforms of SPHK, SPHK1 and SPHK2, have been identified & characterized from mammalian cells. Among them, SPHK1 has been implicated to...

17-phenyl trinor Prostaglandin E2 (17-phenyl trinor PGE2) is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist. 17-phenyl trinor PGE2 causes contraction of the guinea pig ileum at a concentration of 11 µM. It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus. With an ED50...

Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and...

Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid (Cay-20250) by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is...

Sirtuin 5 (SIRT5) is an enzyme that catalyzes the NAD-dependent removal of malonyl, succinyl, and glutaryl groups from target proteins. Although it was originally characterized as a class III histone deacetylase (HDAC), SIRT5 exhibits weak NAD-dependent deacetylase activity in vitro and in vivo. SIRT5 is localized...

Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL-33 is converted by CASP1 to a 18 kDa protein. IL-33 binds to and signals through ST2 (IL1R1) and its stimulation...