Glucose-6-phosphate dehydrogenase (G6PDH) is a cytosolic enzyme that catalyzes the first step in the pentose phosphate pathway. This pathway includes converting glucose to ribose-5-phosphate, a precursor to RNA, DNA, ATP, CoA, NAD, and FAD. The pathway also generates NADPH. G6PDH deficiency, the most common enzyme...

NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis. NDGA inhibits A-23187-induced CysLT biosynthesis in rat peritoneal cells with an IC50 value of 5-7 µM. The IC50 values are 3.0-5.0 µM for human platelet 12-LO and 0.91 µM for rabbit reticulocyte 15-LO.Formal...

APHS is an O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and -2, with IC50 values of 17 and 0.8 µM for human recombinant COX-1 and -2, respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of...

Corey lactone aldehyde benzoate is a versatile, chiral intermediate used in the preparation of prostaglandins and prostaglandin analogs.Formal Name: [3aR-(3aalpha,4alpha,5beta,6aalpha)]5-(benzoyloxy)hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde. CAS Number: 39746-01-5. Molecular Formula: C15H14O5. Formula...

Protein Carbonyl Hydrochloric Acid (Fluorometric) has been tested and formulated to work exclusively with Cayman's Protein Carbonyl Fluorometric Assay Kit (Cay-701530). Please visit Protein Carbonyl Fluorometric Assay Kit (Cay-701530) for the kit protocol, procedures, and product handling.Formulation: 1.4 M...