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S5369-95C-P.100
Sp1 (SP1, Sp1 transcription factor , HGNC:11205) (Control Peptide)
USBio
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100 µg

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347 €

Sp1 (SP1, Sp1 transcription factor , HGNC:11205) (Control Peptide)


ELISA Erklärungen der Abkürzungen ansehen.

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [The UniProt Consortium]


UniProt ID: P08047

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