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Sp1 (SP1, Sp1 transcription factor , HGNC:11205) (Control Peptide)

ART NR.: S5369-95C-P.100 (100 µg)

Hersteller: USBio

Datenblatt

Anwendungen: ELISA

Format: highly purified

UniProt ID: P08047
Suche mit UniProt ID

Geninformationen: GeneID 6667

Schlagworte: TSFP1, Transcription factor Sp1

100 µg

347 €

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Bemerkungen: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [The UniProt Consortium]

Spezifikationen

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