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| S5369-95C-P.100 |
Sp1 (SP1, Sp1 transcription factor , HGNC:11205) (Control Peptide) |
USBio |
100 µg |
365 €
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ELISA  Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [The UniProt Consortium] UniProt ID: P08047  Loading ...- Geninformationen GeneID 6667 Weitere Produkte für dieses Protein:Antibodies
siRNA Relevant Pathways:Products for: SP1 - transcription factor Sp1Schlagworte: TSFP1, Transcription factor Sp1 | |||||
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Datenbank vom 14.06.2013, 14:39 Uhr Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer |
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