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Item number: Cay16136-100

Sotalol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs, IC50s = 8.9 and 5.2 µM for beta1- and beta2-ARs, respectively) and a class III antiarrhythmic agent. It decreases delayed outward potassium currents (IK) in guinea pig ventricular cells and prolongs action potential duration in...

Keywords:	(±)-Sotalol, DL-Sotalol, MJ1999, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride
Application:	beta1/2-adrenergic receptor antagonist
CAS	959-24-0
MW:	308.8 D

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