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Sonic Hedgehog, mouse recombinant (rmSHH)

Item number: 08546.5

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...

Keywords:	SHH, HHG-1, HHG1, Sonic hedgehog protein
Application:	Cell culture
Expressed in:	E.coli
Origin:	mouse
MW:	19800.00 D

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