Soluble CD40 Ligand, His Tag, human recombinant (rHuTRAP-His)

Soluble CD40 Ligand, His Tag, human recombinant (rHuTRAP-His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97284.5 5 µg - -

3 - 10 business days*

94.00€
97284.20 20 µg - -

3 - 10 business days*

208.00€
97284.1 1 mg - -

3 - 10 business days*

3,952.00€
 
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the... more
Product information "Soluble CD40 Ligand, His Tag, human recombinant (rHuTRAP-His)"
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Human recombinant sCD40 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 149 amino acids fragment (113-261) corresponding to the receptor binding domain of the sCD40L protein, having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
Keywords: CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L, CD40LG
Supplier: Biomol GmbH
Supplier-Nr: 97284

Properties

Application: Bioassay
Conjugate: No
Host: E.coli
Species reactivity: human
Purity: >95%
Format: Purified

Database Information

KEGG ID : K03161 | Matching products
UniProt ID : P29965 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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