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Sodium 4-Phenylbutyrate
Sodium 4-Phenylbutyrate

Item number: Cay11323-1

Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins. It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors. Formulations containing sodium...
Keywords: Benzenebutanoic Acid, NSC 657802, TriButyrate, benzenebutanoic acid, monosodium salt
Application: Chemical chaperone, HDAC inhibitor
CAS 1716-12-7
MW: 186.2 D
From 40.00€ *
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IM-54
IM-54

Item number: Cay13323-1

IM-54 is an indolylmaleimide derivative which, at 1 µM, inhibits necrotic cell death induced by H2O2 in promyelocytic leukemia HL-60 cells. It does not prevent etoposide-induced apoptosis and does not inhibit protein kinase C or S6 kinase 1.Formal Name:...
Keywords: 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione
Application: Necrotic cell death inhibitor
CAS 861891-50-1
MW: 325.4 D
From 42.00€ *
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2,4-Dimethylthiazole-5-Carboxylic Acid
2,4-Dimethylthiazole-5-Carboxylic Acid

Item number: Cay13233-500

2,4-Dimethylthiazole-5-carboxylic acid is a highly functionalized and biased thiazole used for drug discovery. It is used as a heterocyclic building block to specifically modify lead compounds.Formal Name: 2,4-dimethyl-5-thiazolecarboxylic acid. CAS Number: 53137-27-2. Molecular Formula: C6H7NO2S. Formula Weight:...
Keywords: 2,4-dimethyl-5-thiazolecarboxylic acid
Application: Drug discovery, Building block
CAS 53137-27-2
MW: 157.2 D
From 22.00€ *
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