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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S1014-53T.100 | 100 µg | - | - |
3 - 19 business days* |
537.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of... more
Product information "Smad3, Recombinant, Human, aa1-425, His-tag (Small Mothers Against Decapentaplegic Deleted in Pancr"
SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding aa1-425 from human SMAD3, his-tagged, expressed in E. coli (NP_005893)., AA sequence:, MGSSHHHHHH SSGLVPRGSH MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRSLDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI, PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN PMSPAHNNLD LQPVTYCEPA FWCSISYYEL NQRVGETFHASQPSMTVDGF TDPSNSERFC LGLLSNVNRN AAVELTRRHI GRGVRLYYIG GEVFAECLSD SAIFVQSPNC NQRYGWHPAT VCKIPPGCNL, KIFNNQEFAA LLAQSVNQGF EAVYQLTRMC TIRMSFVKGW GAEYRRQTVT STPCWIELHL NGPLQWLDKV LTQMGSPSIR CSSVS, Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Mad3, MADH3, Smad3, SMAD3, hSMAD3, SMAD 3, hMAD-3, JV15-2, MAD homolog 3, SMAD family member 3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3 |
Supplier: | United States Biological |
Supplier-Nr: | S1014-53T |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
KEGG ID : | K23605 | Matching products |
UniProt ID : | P84022 | Matching products |
Gene ID | GeneID 4088 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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