- Search results for Cay16974-0.5
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2 products were found matching "Cay16974-0.5"!
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Item number: Cay16974-10
Skepinone-L is an ATP-competitive inhibitor of p38 MAPK isoform p38alpha (IC50s = 5 nM) and p38beta (97% inhibition at 1 µM). It has little effect on a range of other kinases, including p38gamma and p38delta. Skepinone-L dose-dependently blocks the phosphorylation of heat shock protein 27 (HSP27), a p38 MAPK...
Keywords: | 2-[(2,4-difluorophenyl)amino]-7-[(2R)-2,3-dihydroxypropoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one |
Application: | p38alpha inhibitor |
CAS | 1221485-83-1 |
MW: | 425.4 D |
From 66.00€
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Item number: Cay16970-5
EPI-001 is an androgen receptor antagonist with an IC50 value of approximately 6 µM for inhibition of transactivation of the androgen receptor N-terminal domain (NTD). It inhibits androgen-, FSK-, and IL-6-induced, as well as ligand-independent, prostate-specific antigen (PSA) reporter gene expression in LNCaP cells...
Keywords: | 3-[4-[1-[4-(3-chloro-2-hydroxypropoxy)phenyl]-1-methylethyl]phenoxy]-1,2-propanediol |
Application: | Standard, AR antagonist |
CAS | 227947-06-0 |
MW: | 394.9 D |
From 77.00€
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