Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Lysate. Sensitivity: 80pg/ml. Range: 0.125 to 8ng/ml. Sirtuins (Silent information regulators, SIRTs) deacetylate and/or ADP-ribosylate lysine residues of target proteins in an NAD+dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of SIRT2 achieves neuroprotection and identifies SIRT2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.
Datenblatt ansehen
Manual
Kat #: AG-45A-0030EK-KI01
Menge: 96 wellsBuy Bulk
Preis: 704 €
UniProt ID: Q8IXJ6 (Protein knowledgebase)
Schlagworte:
Sirt2, SIR2-like Protein 2
Figure legend: Datenblatt ansehen
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-SIRT 2 (Sirtuin 2, Sirtuin-2, Sirtuin Type 2, SIRT2, Sir2, NAD-dependent Deacetylase Sirtuin 2, Silencing Information Regulator 2-like, Silent Mating Type Information Regulation 2, Silent Mating Type Information Regulation 2 Homolog, SIR2-like, SIR2L, Kat #: S1013-88D4.100
- Anti-Sirt2, Kat #: A300-703A
- Anti-SIRT2, Kat #: WA-AJ1718a
- Anti-Sirt2, Kat #: A300-702A
- Anti-SIRT2 (C), Kat #: AC-R2347-2
- Anti-SIRT2 (C-term), Kat #: WA-AJ1718b
- Anti-SIRT2 (monoclonal) (M01), Kat #: WA-AT3891a
- Anti-Sirtuin 2 (human), Kat #: AG-25A-0083-C100
- Anti-Sirtuin 2 (human), clone S2R233-1, Kat #: AG-20A-0076-C100
- Sirt2 Antibody AbVantage(TM) Pack, Kat #: A310-210A
Enzymes & Proteins
- SIRT 2, Recombinant, Human (Sirtuin 2, Silent Mating Type Information Regulation 2, S. cerevisiae Homolog 2), Kat #: S1013-88C.100
- SIRT2 (human recombinant), Kat #: Cay10011191-25
- SIRT2 (human recombinant), Kat #: Cay10011191-50
- SIRT2 (human recombinant), Kat #: Cay10011191-100
- SIRT2 Direct Assay Reagent (human recombinant), Kat #: Cay700282-1
- SIRT2, aa1-352, Recombinant, Human (Sirtuin 2, SIR2, FLJ35621, FLJ37491, NAD-dependent Deacetylase Sirtuin-2, SIR2L, SIR2-like Protein 2, SIR2L2), Kat #: S1013-88C2.10
- Sirtuin 2 (human, rec.) (His), Kat #: AG-40A-0121-C010
- Sirtuin 2 (human, rec.) (His), Kat #: AG-40A-0121-C050
- Sirtuin 2, active human recombinant protein, Kat #: BPS-50013
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Products for: SIRT2, SIR2L2 - NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-]
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