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Sirtuin 2 (human) (IntraCellular) ELISA Kit (96 wells)

ART NR.: AG-45A-0030EK-KI01 (96 wells)

Hersteller: Adipogen

Datenblatt



Manual



MSDS

Anwendungen: ELISA

Messtechnik: Photometric

UniProt ID: Q8IXJ6
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Schlagworte: Sirt2, SIR2-like Protein 2

96
wells

704 €

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Bemerkungen: Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Lysate. Sensitivity: 80pg/ml. Range: 0.125 to 8ng/ml. Sirtuins (Silent information regulators, SIRTs) deacetylate and/or ADP-ribosylate lysine residues of target proteins in an NAD+dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of SIRT2 achieves neuroprotection and identifies SIRT2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.
Image Art AG-45A-0030EK-KI01 Adipogen Sirtuin 2 (human) (IntraCellular) ELISA Kit (96 wells)
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