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Sirtuin 2 (human) (IntraCellular) ELISA Kit (96 wells)
Apoptosis, Cell Cycle, DNA human
Erklärungen der Abkürzungen ansehen.
solid phase Photometr. Immunological Lysates, Fluids ELISAErklärungen der Abkürzungen ansehen. Adipogen
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AG-​45A-​0030EK-​KI01 96 wells

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704 €In Warenkorb aufnehmen

Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Lysate. Sensitivity: 80pg/ml. Range: 0.125 to 8ng/ml. Sirtuins (Silent information regulators, SIRTs) deacetylate and/or ADP-​ribosylate lysine residues of target proteins in an NAD+dependent manner. Sirtuins are critical regulators of many cellular processes, including insulin secretion, the cell cycle and apoptosis. Sirtuins, in particular SIRT1, emerged as critical regulators of longevity and aging in several model organisms. Furthermore, a variety of age-​associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of SIRT2 achieves neuroprotection and identifies SIRT2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.

Datenblatt ansehen
Manual
Kat #:
AG-45A-0030EK-KI01
Menge:
96 wells

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Preis:
704 €

UniProt ID: Q8IXJ6 (Protein knowledgebase)

Schlagworte:
Sirt2, SIR2-​like Protein 2
Image Art AG-45A-0030 Adipogen Sirtuin 2 (human) (IntraCellular) ELISA Kit (96 wells)
Figure legend: Datenblatt ansehen

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Products for: SIRT2, SIR2L2 - NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-]




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