Sincalide

Sincalide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
LKT-S3351.500 500 µg -

3 - 8 business days*

208.00€
LKT-S3351.1 1 mg -

3 - 8 business days*

346.00€
 
Sincalide is an octapeptide fragment of cholestocystokinin (CCK) that activates the CCK receptor... more
Product information "Sincalide"
Sincalide is an octapeptide fragment of cholestocystokinin (CCK) that activates the CCK receptor on immune cell surfaces. Sincalide is more potent when sulfated. Sincalide exhibits neuroprotective, immunosuppressive, and anorexigenic activities. In hippocampal neurons, sincalide increases the density of filopodia and dendritic spines. In vagal motor neurons, sincalide increases excitatory currents. In other cellular models, this compound inhibits IgG1 production and regulates transcription factor expression and activation of B cells. Sincalide also modulates hormone signaling, increasing adrenocorticotropic hormone (ACTH) secretion and altering leptin, melanocortin, and corticotropin-releasing factor (CRF) pathways. In separate animal models, sincalide decreases appetite and increases cardiac output, also increasing gastrointestinal blood flow.
Keywords: Cholecystokinin, CCK Octapeptide (26-33), CCK8
Supplier: LKT Laboratories
Supplier-Nr: S3351

Properties

Application: Metabolic studies
Conjugate: No
MW: 1143,29 D

Database Information

CAS : 25126-32-3| Matching products
KEGG ID : K05226 | Matching products
UniProt ID : P06307 | Matching products
Gene ID GeneID 885 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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