4 products were found matching "Cay11754"!

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Sesamolin
Sesamolin

Item number: Cay11754-5

Sesamolin is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro. In vivo, sesamolin reduces epididymal white adipose tissue weight and serum triacylglcerol,...
Keywords: 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
Application: Lipid peroxidation inhibitor
CAS 526-07-8
MW: 370.4 D
From 32.00€ *
Review
Erastin
Erastin

Item number: Cay17754-5

Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...
Keywords: 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Application: Antitumor agent
CAS 571203-78-6
MW: 547.1 D
From 60.00€ *
Review
Carfilzomib
Carfilzomib

Item number: Cay17554-5

Carfilzomib is a second-generation, irreversible, peptide epoxyketone class proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and the beta5i subunit of the immunoproteasome 20Si (LMP7, IC50 = 14 nM) with minimal cross reactivity to other...
Keywords: PR-171,...
Application: Proteasome PSMB5 inhibitor
CAS 868540-17-4
MW: 719.9 D
From 43.00€ *
Review
VEGFR2 Kinase Inhibitor II
VEGFR2 Kinase Inhibitor II

Item number: Cay17544-5

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's...
Keywords: (3Z)-5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-2H-indol-2-one
Application: VEGFR2 inhibitor
CAS 288144-20-7
MW: 343.2 D
From 114.00€ *
Review