6 products were found matching "Cay10764-25"!
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RIZ1 (human recombinant)
Item number: Cay10765-250
Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor...
| Keywords: | KMT8, PRDM2, MTB-ZF, MTB-ZF, MTE-binding protein, MTE-binding protein, Zinc finger protein RIZ, Zinc finger protein RIZ,... |
| Application: | Methylation studies |
| Expressed in: | E.coli |
| MW: | 49,5 kD |
481.00€
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APD668
Item number: Cay17642-5
GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic beta-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine (Cay-10172) and oleoyl ethanolamide (Cay-90265) increases intracellular cAMP levels and...
| Keywords: | JNJ-28630368, 4-[[1-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]-1-piperidinecarboxylic acid,... |
| Application: | GPR119 agonist |
| CAS | 832714-46-2 |
| MW: | 477.5 D |
From 60.00€
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CAY10640
Item number: Cay10642-5
Soluble epoxide hydrolase (sEH) inhibitors have important therapeutic use by increasing the in vivo concentration of EETs and other fatty acid epoxides, resulting in anti-inflammatory, antihypertensive, neuroprotective, and cardioprotective effects. CAY10640 is a 1-aryl-3-(1-acylpiperidin-4-yl)urea analog that...
| Keywords: | sEHi, Soluble Epoxide Hydrolase Inhibitor, N-[1-(cyclopropylcarbonyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea |
| Application: | Soluble epoxide hydrolase (sEH) inhibitor |
| CAS | 1208549-68-1 |
| MW: | 371.4 D |
From 73.00€
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(±)7(8)-EpDPA
Item number: Cay10465-25
Docosahexaenoic acid (DHA, Cay-90310) is the most abundant omega-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and...
| Keywords: | (±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy Docosapentaenoic Acid, (±)7,8-epoxy DPA,... |
| Application: | Soluble epoxide hydrolase substrate |
| CAS | 895127-66-9 |
| MW: | 344.5 D |
From 56.00€
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C20 Ceramide (d18:1/20:0)
Item number: Cay10724-5
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway. Certain forms of ceramide have been shown to mediate cellular responses such as apoptosis, growth arrest, and differentiation in certain cell types. C20 Ceramide is a natural 20:0 ceramide...
| Keywords: | Cer(d18:1/20:0), Ceramide (d18:1/20:0), N-arachidoyl-D-erythro-Sphingosine,... |
| Application: | Bioactiv lipid assays |
| CAS | 7344-02-7 |
| MW: | 594 D |
From 24.00€
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PF-04620110
Item number: Cay16425-25
Acyl-CoA:diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final committed step in the biosynthesis of triglycerides and has potential roles in obesity, diabetes, and atherosclerosis. PF-04620110 is a potent inhibitor of DGAT-1 (IC50 = 19 nM) that is without effect on DGAT-2. It has high oral bioavailability...
| Keywords: | trans-4-[4-(4-amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid |
| Application: | DGAT1 inhibitor |
| CAS | 1109276-89-2 |
| MW: | 396.4 D |
From 123.00€
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