SU 1498

SU 1498
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16354-500 500 µg -

6 - 10 business days*

46.00€
Cay16354-1 1 mg -

6 - 10 business days*

86.00€
Cay16354-5 5 mg -

6 - 10 business days*

158.00€
 
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka... more
Product information "SU 1498"
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1, IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases. It effectively blocks signaling through VEGFR2 both in vitro and in vivo. SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.Formal Name: (2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide. CAS Number: 168835-82-3. Synonyms: AG-1498, Tyrphostin SU 1498. Molecular Formula: C25H30N2O2. Formula Weight: 390.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS(pH7.2) (1:2): 0.3 mg/ml, DMSO: 20 mg/ml, Ethanol: 10 mg/ml. lambdamax: 249, 348, 356 nm. SMILES: O=C(/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1)NCCCC2=CC=CC=C2. InChi Code: InChI=1S/C25H30N2O2/c1-17(2)22-14-20(15-23(18(3)4)24(22)28)13-21(16-26)25(29)27-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-15,17-18,28H,8,11-12H2,1-4H3,(H,27,29)/b21-13+. InChi Key: JANPYFTYAGTSIN-FYJGNVAPSA-N.
Keywords: AG-1498, Tyrphostin SU 1498, (2E)-2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide
Supplier: Cayman Chemical
Supplier-Nr: 16354

Properties

Application: VEGFR2 inhibitor
MW: 390.5 D
Formula: C25H30N2O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 168835-82-3| Matching products
KEGG ID : K05098 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H312, H315, H319, H332, H335
P Phrases: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P361+364, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "SU 1498"
Write a review
or to review a product.
Viewed