ST2 (human):Fc (human, rec.)

ST2 (human):Fc (human, rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-40A-0059-C050 50 µg -

3 - 9 business days*

462.00€
 
Signal peptide and the sequence of isoform 2 of human ST2 (amino acids 1-328) are fused at the... more
Product information "ST2 (human):Fc (human, rec.)"
Signal peptide and the sequence of isoform 2 of human ST2 (amino acids 1-328) are fused at the C-terminus to the Fc portion of human IgG1. Interacts with human IL-33. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. The ST2 (Interleukin-1 receptor-like 1, Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
Keywords: Interleukin-1 Receptor-like 1, IL-1 Receptor-like 1, IL1RL1, IL-33 Receptor, Interleukin-33 Receptor
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40A-0059

Properties

Application: Bioassays
Conjugate: No
Host: Human cells
Species reactivity: human
MW: 90 kD
Format: Liquid

Database Information

KEGG ID : K05171 | Matching products
UniProt ID : Q01638 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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