10 products were found matching "045313.50"!

Most phosphorylation occurs on serine and threonine, with less than 1% on tyrosine. Tyrosine phosphorylation is involved in regulating a variety of cellular processes. In particular, protein tyrosine phosphorylation is important for signaling pa

WB 1:500 - 1:2000. Protein function: Dephosphorylates and concomitantly deactivates CaM- kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis. [The UniProt Consortium]

Acetylation is an important modification of proteins in cell biology. Acetylation occurs in thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. Among these proteins, chromatin pro

WB 1:500 - 1:2000. Protein function: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a...

MGLL is membrane-associated member of the serine hydrolase superfamily. MGLL functions together with hormone-sensitive lipase (LIPE) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL) in completing hydrolysis of...

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often...

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any...

Protein Construction: Recombinant Mouse Receptor-type Tyrosine-protein Phosphatase C is produced by our Mammalian expression system and the target gene encoding Gln26­Lys566 is expressed with a 6His tag at the C-terminus. Sequence: Gln26­-Lys566. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL...

WB 1:200 - 1:2000. Protein function: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). [The UniProt Consortium]

Protein function: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5- trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1...