ST2 is a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP,...

ST2 is a membrane protein belonging to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. ST2, also known as IL1RL1, is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by...

Intended Use:, The ST2, Mouse BioAssay(TM) ELISA Kit is a 4.5 hour solid phase ELISA designed to measure mouse ST2 in cell culture supernates, serum, and plasma. Test Principle: This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for mouse ST2 has been pre-coated...

ST2V is a 259aa membrane protein belonging to the interleukin 1 receptor family with two transmembrane helices, one TIR domain and three Ig-like C2-type (immunoglobulin-like) domains. ST2V is a novel variant of human ST2 which has isoforms ST2L, ST2S, ST2V and ST2LV. It is usually expressed in the human leukemic...

ST7 (Suppressor of Tumorigenicity 7), also known as RAY1, TSG7 and FAM4A1, is a type I transmembrane protein belonging to the LDLR superfamily and is designated LRP12. The human ST7 cDNA encodes 859aa including a 32aa signal sequence, a 460aa extracellular domain (ECD) containing two CUB domains and five LDLR class...