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Item number: SYN-1133-M100

Soluble in DMSO. JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with an IC(50) of 40nM. It also inhibits closely related tyrosine kinases such as Ret (IC(50) of 180nM) and Kit (C50 of 500nM). It has no significant activity (>1µM) against VEGFR-1 and VEGFR-3. Target: VEGFR-2 ,...

Keywords:	JNJ38158471
Application:	VEGFR-2 inhibitor
CAS	951151-97-6
MW:	364,8 D

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