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SLF
SLF

Item number: Cay10007974-10

FK-506 is a potent immunosuppressant that forms a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex inhibits the activity of the calcium/calmodulin-dependent protein phosphatase, calcineurin, leading to disruption of T-cell activation. Synthetic ligand of FKBP (SLF) is a...
Keywords: Synthetic Ligand of FKBP, 1-(3,3-dimethyl-1,2-dioxopentyl)-(2S)-2-piperidinecarboxylic acid,...
Application: FK-506 analog
CAS 195513-96-3
MW: 524.7 D
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