16 products were found matching "Cay13411"!

Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 µM) and calcium/calmodulin kinase II...

An anthroquinone derivative that is naturally found in the flower of H. perforatum (St. John's wort) and has antidepressant, antiviral, and anticancer activities. Hypericin inhibits neuronal uptake of serotonin, norepinephrine, dopamine, GABA and L-glutamate, contributing to its antidepressant effects. It exerts...

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins...

Goat anti-mouse IgG conjugated to SureLight(R) P3 Antibody: Goat polyclonal anti-Mouse IgG Dye: SureLight(R) P3 Excitation max. lambda: 614 nm Emission max. lambda: 662 nm Isotype: IgG Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 662 nm. Excitation: 614 nm. Formulation:...

Transforming growth factor-beta (TGF-beta) signals through a cell surface heteromeric complex involving type I (TGF-beta RI) and type II (TGF-beta RII) receptors. Downstream signal transduction is mediated by the TGF-beta RI kinase domain through the phosphorylation of Smad proteins. LY364947 is a selective...

Goat anti-Mouse IgG1 conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Mouse IgG1 Dye: SureLight(TM) R-phycoerythrin (R-PE) Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm. Excitation:...

Goat Anti-Chicken IgY conjugated to SureLight(TM) R-PE, 100µg Antibody: Goat polyclonal Anti-Chicken IgY Isotype: IgY Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm. Excitation: 565>498 nm. Formulation: (Request formulation change), A lyophilized powder. Storage...

Goat anti-Llama IgG conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Llama IgG Isotype: IgG Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm. Excitation: 565>498 nm. Formulation: (Request formulation change), A lyophilized powder. Storage Buffer: 100...

Goat anti-Mouse IgG2a conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Mouse IgG2a Isotype: IgG2A Dye: SureLight(TM) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm....

Goat anti-Mouse IgG2b conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Mouse IgG2b Dye: SureLight(TM) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses:Flow cytometry, fluorescence-activated cell sorting, protein microarrays, and luminexEmission: 578 nm. Excitation:...

NVP-AEW541 is an inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50 = 0.15 µM in a cell-free assay). It is selective for IGF-1R over a panel of 20 kinases but also inhibits the insulin receptor (InsR), VEGFR1, FMS-related tyrosine kinase 3 (FLT3), and tunica interna endothelial cell kinase 2 (Tie2,...

Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Prostaglandin free acids generally bind to their cognate receptors with 10 to 100 times the affinity of the corresponding ester...