4 products were found matching "Cay10011194-25"!

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Elesclomol
Elesclomol

Item number: Cay10011192-5

Elesclomol is an inducer of apoptosis and a copper ionophore. It induces the production of reactive oxygen species (ROS) and increases oxidative stress response gene expression in Ramos (RA 1) B cell lymphoma cells when used at a concentration of 500 nM. Elesclomol (100 nM) disrupts the mitochondrial membrane...
Keywords: NSC 174939, STA 4783, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide]-propanedioic acid
Application: Antitumor agent, apoptosis inducer
CAS 488832-69-5
MW: 400.5 D
From 84.00€ *
Review
Trimidox (hydrochloride)
Trimidox (hydrochloride)

Item number: Cay10011124-25

Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in...
Keywords: CF 233 (hydrochloride), N,3,4,5-tetrahydroxy-benzenecarboximidamide, monohydrochloride
Application: Ribonucleotide reductase inhibitor
CAS 95933-75-8
MW: 220.6 D
From 86.00€ *
Review
SIRT3 (human, recombinant)
SIRT3 (human, recombinant)

Item number: Cay10011194-100

The sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human...
Keywords: SIRT3, SIR2L3, hSIRT3, hSIRT3, SIR2-like protein 3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, Regulatory...
Application: WB
MW: 37 kD
642.00€ *
Review
LDL Uptake Cell-Based Assay Kit
LDL Uptake Cell-Based Assay Kit

Item number: Cay10011125-1

Low-density lipoproteins (LDL) is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL is taken up by hepatic and extrahepatic tissues through LDL receptor-mediated endocytosis where it is internalized and degraded to free cholesterol and amino acids. Uptake of...
Keywords: Low-Density Lipoprotein Uptake
Application: FC, fluorescence
554.00€ *
Review