- Search results for Cay10011194-25
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4 products were found matching "Cay10011194-25"!
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Item number: Cay10011192-5
Elesclomol is an inducer of apoptosis and a copper ionophore. It induces the production of reactive oxygen species (ROS) and increases oxidative stress response gene expression in Ramos (RA 1) B cell lymphoma cells when used at a concentration of 500 nM. Elesclomol (100 nM) disrupts the mitochondrial membrane...
Keywords: | NSC 174939, STA 4783, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide]-propanedioic acid |
Application: | Antitumor agent, apoptosis inducer |
CAS | 488832-69-5 |
MW: | 400.5 D |
From 84.00€
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Item number: Cay10011124-25
Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in...
Keywords: | CF 233 (hydrochloride), N,3,4,5-tetrahydroxy-benzenecarboximidamide, monohydrochloride |
Application: | Ribonucleotide reductase inhibitor |
CAS | 95933-75-8 |
MW: | 220.6 D |
From 86.00€
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Item number: Cay10011194-100
The sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human...
Keywords: | SIRT3, SIR2L3, hSIRT3, hSIRT3, SIR2-like protein 3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, Regulatory... |
Application: | WB |
MW: | 37 kD |
642.00€
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Item number: Cay10011125-1
Low-density lipoproteins (LDL) is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL is taken up by hepatic and extrahepatic tissues through LDL receptor-mediated endocytosis where it is internalized and degraded to free cholesterol and amino acids. Uptake of...
Keywords: | Low-Density Lipoprotein Uptake |
Application: | FC, fluorescence |
554.00€
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