4 products were found matching "Cay10011566"!

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SIRT3 Direct Fluorescent Screening Assay Kit

Item number: Cay10011566-96

The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. SIRT3 is a mitochondrial protein that plays a role in metabolic regulation and other cellular...

Keywords:	SIRT3, hSIRT3, SIR2L3, EC=3.5.1.-, SIR2-like protein 3, NAD-dependent deacetylase sirtuin-3, mitochondrial
Application:	SIRT3 activator/inhibitor screening
Species reactivity:	human

467.00€ *

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Ramatroban

Item number: Cay10156-5

Ramatroban is a dual TP and DP2/CRTH2 receptor antagonist (Kis = 4.5 and 4.3 nM for the human receptors, respectively). It is selective for these receptors over the prostaglandin E2 (PGE2) receptor subtypes EP1 and EP2, as well as the FP and IP receptors, at 1 µM. Ramatroban inhibits contractions induced by U-46619...

Keywords:	Ramatroban, 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
Application:	DP2 receptor antagonist
CAS	116649-85-5
MW:	416.5 D

From 43.00€ *

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HDAC Fluorometric Activity Assay Kit

Item number: Cay10011563-96

Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Transcriptional...

Keywords:	Histone Deacetylase
Application:	HDAC activity measurement

436.00€ *

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HDAC1 Inhibitor Screening Assay Kit

Item number: Cay10011564-96

Keywords:	Histone Deacetylase 1
Application:	HDAC1 inhibitor screening
Species reactivity:	human

467.00€ *

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