11 products were found matching "Cay10010991"!
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SIRT1 FRET-Based Screening Assay Kit
Item number: Cay10010991-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Sir2 (Silent information regulator 2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Keywords: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
| Application: | SIRT1 inhibitor/activator screening |
| Species reactivity: | human |
467.00€
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W123
Item number: Cay10010992-1
Sphingosine-1-phosphate (S1P) modulates skin, vascular endothelial, and immune cells via five distinct G protein-coupled receptors. The S1P type 1 receptor, S1P1, also known as EDG-1, mediates endothelial, lymphoid, and neuronal cell responses to S1P, as well as the synthetic agonist FTY720. W123 is an analog of...
| Keywords: | 3-(2-(3-hexylphenylamino)-2-oxoethylamino)propanoic acid |
| Application: | S1P1 antagonist |
| CAS | 1345982-24-2 |
| MW: | 306.4 D |
From 115.00€
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SIRT1 (human recombinant) Direct Assay Reagent
Item number: Cay10010994-1
Synonyms: SIRT1 (human recombinant).
| Keywords: | SIRT1 (human recombinant) |
| Application: | Kit component |
43.00€
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SIRT1 Direct Assay Buffer (10X)
Item number: Cay10010993-1
Formulation: 5 ml of 500 mM Tris-HCl, pH 8.0, containing 1.37 M sodium chloride, 27 mM KCl, and 10 mM MgCl2.
| Application: | Kit component |
20.00€
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SIRT1 Direct Nicotinamide
Item number: Cay10010997-1
Formulation: 500 µl of a 50 mM solution of nicotinamide.
| Application: | Kit component |
20.00€
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Oleoyl 3-carbacyclic Phosphatidic Acid
Item number: Cay10010299-1
Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn-2 (2-ccPA) or sn-3 (3-ccPA) linkage, preventing the opening of cPA to produce...
| Keywords: | 3-ccPA 18:1, (9Z)-9-octadecenoic acid, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester |
| Application: | Cyclic LPA analog |
| CAS | 779333-58-3 |
| MW: | 416.5 D |
From 102.00€
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Prostaglandin A2-biotin
Item number: Cay10010499-1
Prostaglandin A2 (PGA2) blocks cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. It has antitumor effects, targeting scaffold/matrix attachment region-binding protein 1 (SMAR1) through an Hsp70-dependent mechanism. PGA2 also induces apoptosis in HL-60 cells. Prostaglandin A2-biotin (PGA2-biotin) is...
| Keywords: | PGA2-biotin, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oyl-N'-biotinoyl-1,5-diaminopentane |
| Application: | Bioactive lipid assays |
| MW: | 644.9 D |
From 50.00€
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