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SIGIRR:Fc, Recombinant, Human (Toll/Interleukin-1...

Item number: 045281.10

SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Sequence: Signal peptide and extracellular domain of human SIGIRR (aa1-118)...

Keywords:	TIR8, SIGIRR, Toll/interleukin-1 receptor 8, Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single...
Origin:	human

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