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1 products were found matching "Cay13967"!
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Item number: Cay13967-10
DOT1L is a protein methyltransferase (PMT). It is the only enzyme known to methylate histone 3 at lysine 79 (H3K79), where it catalyzes mono-, di-, and trimethylation. Proper DOT1L function is necessary for transcriptional activation of many genes, DNA damage repair, and cell cycle regulation. SGC0946 is a potent...
Keywords: | 5-bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-ribofura... |
Application: | Potent DOT1L inhibitor |
CAS | 1561178-17-3 |
MW: | 618.6 D |
From 129.00€
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