- Search results for Cay10319-50
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8 products were found matching "Cay10319-50"!
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Item number: Cay10310-50
Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and...
Keywords: | PGA3, 9-oxo-15S-hydroxy-prosta-5Z,10,13E,17Z-tetraen-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 36614-31-0 |
MW: | 332.4 D |
From 130.00€
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Item number: Cay10319-100
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and...
Keywords: | PRSET7, PR-Set7, PR-Set7, PR/SET07, PR/SET07, H4-K20-HMTase KMT5A, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A,... |
Application: | Enzyme activity |
Expressed in: | E.coli |
MW: | 21.1 kD |
537.00€
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Item number: Cay10009312-50
SKF 96365 inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels with an IC50 value of approximately 10 µM. It inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM. SKF 96365 can distinguish receptor-mediated release in...
Keywords: | 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole, monohydrochloride |
Application: | Calcium influx inhibitor |
CAS | 130495-35-1 |
MW: | 402.9 D |
From 27.00€
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Item number: Cay10009317-50
Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: | Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,... |
Application: | Procaspase-3 activator |
CAS | 315183-21-2 |
MW: | 392.5 D |
From 145.00€
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Item number: Cay10010399-50
SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
Keywords: | 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol |
Application: | MAP kinases Inhibitor |
CAS | 152121-30-7 |
MW: | 331.3 D |
From 39.00€
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Item number: Cay10350-100
Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms....
Keywords: | Interferon receptor 1-bound protein 4, Interferon receptor 1-bound protein 4, Protein arginine N-methyltransferase 1,... |
Application: | Enzyme activity |
Expressed in: | E.coli |
MW: | 69,2 kD |
391.00€
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Item number: Cay10010309-50
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | alphaZ-[(3,4-dimethoxyphenyl)methylene]-3-pyridineacetonitrile |
Application: | EGF receptor kinase inhibitor |
CAS | 149286-90-8 |
MW: | 266.3 D |
From 80.00€
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Item number: Cay10010329-50
Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of...
Keywords: | HDBA, NSC 666251, 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid |
Application: | Kinase inhibitor |
CAS | 125697-93-0 |
MW: | 275.3 D |
From 35.00€
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