SET8 Methyltransferase Inhibitor Screening Assay Kit

SET8 Methyltransferase Inhibitor Screening Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay700350-96 96 wells -

6 - 10 business days*

922.00€
 
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates... more
Product information "SET8 Methyltransferase Inhibitor Screening Assay Kit"
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 Methyltransferase Inhibitor Screening Assay provides a convenient method for screening human SET8 inhibitors. The transfer of the methyl group from SAM by SET8 (provided in the kit) to the acceptor peptide (H4K20) generates S-adenosylhomocysteine, which is rapidly converted to urate and hydrogen peroxide (H2O2) using an enzyme mixture provided in the kit. The H2O2 formed is quantified using 10-acetyl-3,7-dihydroxyphenoxazine (ADHP) to produce the highly fluorescent compound resorufin (excitation 530-540 nm, emission 585-595 nm).Synonyms: PR-Set7, SETD8, SET domain-containing (lysine methyltransferase) 8.
Keywords: PR-Set7, SET domain-containing (lysine methyltransferase) 8, SETD8
Supplier: Cayman Chemical
Supplier-Nr: 700350

Properties

Application: SET8 inhibitor screening
Format: Homog.

Database Information

KEGG ID : K11428 | Matching products
UniProt ID : Q9NQR1 | Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H227, H302, H315, H316, H319, H320
P Phrases: P210, P264, P270, P280, P301+310, P302+352, P305+351+338, P321, P330, P332+313, P337+313, P362+364, P370+378, P403, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "SET8 Methyltransferase Inhibitor Screening Assay Kit"
Write a review
or to review a product.
Viewed