Source: recombinant N-terminal hexahistidine-tagged SET7/9 amino acids 1-366, purified from E. coli. Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated, and unlike most SET proteins, SET7/9 is exclusively a mono-methylase. SET7/9 methylates histone H3, tumor suppressor p53, and transcription factor TAF10. Recently, SET7/9 was shown to catalyze methylation of p53 in response to DNA damage thereby activating p53 for subsequent acetylation. SET7/9 is able to modulate p53 activity in a human cancer cell line, implying that it may play a significant role in human tumorigenesis.
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Kat #: Cay10320-50
Menge: 50 µgBuy Bulk
Preis: 72 €
UniProt ID: Q8WTS6 (Protein knowledgebase)
Schlagworte:
Histone-lysine N-methyltransferase SETD7, EC=2.1.1.43, KMT7, SETD7/9, SET Domain-containing Protein 7/9 Loading ...
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-SET7, Kat #: A301-747A
- Anti-SET7 (C-term), Kat #: WA-AP1194d.20
- Anti-SET7 (C-term), Kat #: WA-AP1194d
- Anti-SET7 (IHC), Kat #: IHC-00616
- Anti-SET7 (N-term), Kat #: WA-AP1194a.20
- Anti-SET7 (N-term), Kat #: WA-AP1194a
- Anti-SET7 (SET Domain Containing Protein 7, SET Domain-containing Protein 7, SET7/9, SET9, SETD7, FLJ21193, H3-K4-HMTase, H3 Lysine-4 Specific, Histone H3 K4 Methyltransferase, Histone H3-K4 Methyltransferase, Histone H3 Lysine 4 Specific Methyltransferas, Kat #: S1012-22A.100
- Anti-SET7 (SET9) (Center), Kat #: WA-AP1194c
- Anti-SET7 (SET9) (Center), Kat #: WA-AP1194c.20
- Anti-SET7, CT (Histone H3-K4 Methyltransferase SETD7, H3-K4-HMTase SETD7, SET Domain-Containing Protein 7, Set9, SET7/9, Lysine N-methyltransferase 7, Histone-lysine N-methyltransferase SETD7, KMT7, KIAA1717), Kat #: S1012-27C.100
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Products for: SETD7 - histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43]
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