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SCF (human):Fc (mouse) (rec.)

ART NR.: CHI-HF-211SCF-C050 (50 µg)

Hersteller: Chimerigen


Anwendungen: Bioassays

Exprimiert in: Hamster cells

Ursprungs-Art: human

Reinheit: >98%

Format: lyophilized

Lagerung: -20°C

Versand: +4°C

UniProt ID: P21583 | Suche mit UniProt ID

Gene ID: Gene ID 4254 | Suche mit Gene ID

KEGG ID: K05461 | Suche mit KEGG ID

Schlagworte: MGF, SCF, KITLG, sKITLG, Kit ligand, c-Kit ligand, Stem cell factor, Soluble KIT ligand, Mast cell growth factor


50 µg

286 €

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Bemerkungen: The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.

Die Preise verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.

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