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SC-236
SC-236

Item number: Cay10004219-10

The physiologic roles and importance of constitutive COX-1 and inducible COX-2 have been reviewed. SC-236 is a potent, selective, orally active inhibitor of COX-2 with an IC50 of 10 nM and approximately 18,000-fold COX-2 selectivity. SC-236 has a long plasma half-life and can be dosed once daily (20 mg/kg) in...
Keywords: 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide
Application: COX-2 inhibitor
CAS 170569-86-5
MW: 401.8 D
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