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SB-258585 (hydrochloride)
SB-258585 (hydrochloride)

Item number: Cay17416-10

SB-258585 is a potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53). It displays over 100-fold selectivity for 5-HT6 over other 5-HT, dopamine, and alpha-adrenergic receptors. Radiolabeled forms of SB-258585 have been used to evaluate other potential ligands of the 5-HT6 receptor. SB-258585 has...
Keywords: 4-iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-benzenesulfonamide, monohydrochloride
Application: 5-HT6 receptor antagonist
CAS 1216468-02-8
MW: 523.8 D
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