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S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea...

Item number: Cay81280-25

EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 µM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake.Formal...

Keywords:	EPIT, ethyl[4-(trifluoromethyl)phenyl] carbamimidothioate, hydrochloride
Application:	nNOS inhibitor
CAS	163490-78-6
MW:	284.7 D

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