S-ethyl Isothiourea (hydrobromide)

S-ethyl Isothiourea (SEIT) is a potent inhibitor of NOS in vitro but lacks good in vivo efficacy due to poor cellular penetration. The Ki values are 19, 39, and 29 nM using purified human iNOS, eNOS, and nNOS, respectively.Formal Name: ethyl carbamimidothioate, hydrobromide. CAS Number: 1071-37-0. Synonyms: Ethiron bromide, 2-Ethyl-2-thiopseudourea hydrobromide, SEIT (HBr), WR 539. Molecular Formula: C3H8N2S . HBr. Formula Weight: 185.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: N/C(SCC)=N/[H].Br. InChi Code: InChI=1S/C3H8N2S.BrH/c1-2-6-3(4)5,/h2H2,1H3,(H3,4,5),1H. InChi Key: SWXXKWPYNMZFTE-UHFFFAOYSA-N.