(S)-Lisofylline

(S)-Lisofylline
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13617-1 1 mg -

6 - 10 business days*

96.00€
Cay13617-5 5 mg -

6 - 10 business days*

419.00€
Cay13617-10 10 mg -

6 - 10 business days*

742.00€
 
LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (S)-LSF is... more
Product information "(S)-Lisofylline"
LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (S)-LSF is the pharmacologically inactive optical enantiomer of (R)-LSF, the biologically active isomer. When metabolized by isolated human liver cells, pentoxifylline is exclusively reduced to (S)-LSF in the cytosol, while reduction in liver microsomes is 85% stereoselective in favor of (S)-LSF formation. Thus, pentoxifylline is an inefficient prodrug for the delivery of therapeutically relevant lisofylline.Formal Name: 3,7-dihydro-1-[5S-hydroxyhexyl]-3,7-dimethyl-1H-purine-2,6-dione. CAS Number: 100324-80-9. Synonyms: (+)-Lisofylline, (S)-LSF. Molecular Formula: C13H20N4O3. Formula Weight: 280.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 12 mg/ml, DMSO: 3 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 273 nm. SMILES: O=C(N(C)C1=C2N(C)C=N1)N(CCCC[C@@H](O)C)C2=O. InChi Code: InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m0/s1. InChi Key: NSMXQKNUPPXBRG-VIFPVBQESA-N.
Keywords: (+)-Lisofylline, (S)-LSF, 3,7-dihydro-1-[5S-hydroxyhexyl]-3,7-dimethyl-1H-purine-2,6-dione
Supplier: Cayman Chemical
Supplier-Nr: 13617

Properties

Application: Anti-inflammatory agent
MW: 280.3 D
Formula: C13H20N4O3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 100324-80-9| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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